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31 December, 2019 China alerts the World Health Organization (WHO) to dozens of instances it has recorded of “viral pneumonia” within the Wuhan metropolis area.

10 February, 2020 Public Health England rolls out coronavirus checks to 12 UK laboratory websites.

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11 March, 2020 The World Health Organisation declares Covid-19 a pandemic.

Covid-19 lateral circulate check package. Picture: Simon Burt/Shutterstock

23 March, 2020 UK goes into lockdown.

23 March, 2020 Roslin researcher Dr Kenneth Baillie is introduced because the lead on a £5 million examine to look at the impact of coronavirus an infection on the human physique.

Researchers will gather samples and information from 1,300 Covid-19 sufferers within the UK.

April, 2020 Scientists from the University of Edinburgh and NHS Lothian be part of a UK consortium analysing the genetic code of Covid-19 to map the way it spreads.

Pfizer-BioNTech COVID-19 Vaccine “comirnaty” ampoule. Picture: Daniel Chetroni/Shutterstock

8 April, 2020 The University of Glasgow pronounces it’ll host a serious Covid-19 testing facility, on the Queen Elizabeth University Hospital Campus, in collaboration with the Scottish Government and business consultants from BioAscent Discovery and the University of Dundee’s Drug Discovery Unit.

16 April, 2020 Alva-based medical diagnostics firm Omega pronounces it has signed a memorandum of understanding with three different UK corporations, along side the University of Oxford, to type the UK Rapid Test Consortium – which can collectively develop and manufacture a Covid-19 level of care antibody check as a part of the UK Government’s 5 pillar nationwide testing technique.

16 April 2020 Lamellar Biomedical, the Motherwell-based firm pioneering new approaches to respiratory illnesses and complicated lung problems, pronounces the launch of a programme to handle the doubtless deadly penalties of Covid-19 on respiratory operate.

22 April, 2020 The Lighthouse Laboratory in Glasgow – a serious new Covid-19 testing facility – turns into operational. It is a part of what would be the greatest community of diagnostic testing services in British historical past, alongside different Lighthouse Lab websites in Milton Keynes and Alderley Park. The lab will check samples from regional centres the place NHS employees and frontline employees with suspected Covid-19 infections are examined. It is hoped the lab will shortly transfer in direction of processing a number of thousand checks per day, earlier than scaling as much as tens of 1000’s of checks per day.

Picture: Seda Yalova/Shutterstock

4 May, 2020 Scientists on the University of Dundee and the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) publish on-line among the largest and highest decision photos recorded of the SARS-CoV-2 virus, the reason for the Covid-19 pandemic.

The photos had been collected by a consortium of researchers within the Netherlands. They present the formation of SARS-CoV-2 particles in a tissue mannequin of the human intestine, as seen by an ultra-powerful electron microscope.

12 May, 2020 The Universities of Glasgow and Dundee are awarded £225,000 to quickly display for potential Covid-19 remedies. The challenge is funded by the Covid-19 Therapeutics Accelerator, launched by the Bill & Melinda Gates Foundation, Wellcome, and Mastercard, to hurry up the response to the pandemic by funding the identification, evaluation, growth and scale-up of remedies.

28 May, 2020 St Andrews-based Pneumagen (Holdings) pronounces a£4 million funding to permit the medical growth of Neumifil for the prevention and remedy of Covid-19.

The funding is led by Thairm Bio with further funding from the Scottish Investment Bank.

2 June 2020 The University of Dundee’s Drug Discovery Unit (DDU) has acquired €5 million (£4.2m) of funding to develop antiviral remedies for Covid-19 and future coronaviruses.

The funding, by the Covid-19 Therapeutics Accelerator, allows DDU scientists to start work on figuring out novel anti-coronavirus brokers.

The three-year challenge will concentrate on figuring out secure, orally-dosed medicine with the potential to sort out acute infections and scale back transmission within the common inhabitants.

16 June, 2020 The University of Dundee leads the medical trial of a brand new anti-inflammatory drug designed to scale back situations of extreme lung harm and dying in Covid-19 sufferers.

Researchers from the college’s School of Medicine will work with drug growth firm Evgen Pharma to check whether or not the drug, often called SFX-01, improves outcomes for Covid-19 victims.

This examine is supported by a grant from the medical analysis charity LifeArc.

19 June, 2020 A brand new consortium to watch the security and effectiveness of Covid-19 vaccines is shaped by the Medicines Monitoring Unit (MEMO Research), University of Dundee and the Drug Safety Research Unit (DSRU) in Southampton.

Developers of vaccines are required to show high quality, security and efficacy for his or her merchandise earlier than members of the general public begin receiving them.

22 June, 2020 Stirling’s Symbiosis Pharmaceutical Services pronounces it has signed a provide settlement with AstraZeneca for sterile manufacture of the Covid-19 recombinant adenovirus vaccine for firm sponsored medical trials.

Under the settlement, Symbiosis will present AstraZeneca fast-track entry to sterile vaccine drug product manufacturing capability for medical trial provide.

2 July, 2020 Glasgow biotechnology firm TC BioPharm confirms it’s commencing preliminary medical trials on an experimental remedy designed to kill Covid-19 contaminated cells.

TCB is the chief in medical use of gamma-delta T-cells, the primary line of defence in viral an infection and pre-programmed to focus on a variety of illnesses, together with many most cancers varieties.

14 July, 2020 E&O Laboratories in Bonnybridge lands a deal value as much as £7 million with NHS Scotland after making a chemical answer to help the Covid-19 testing course of. The strategy is designed to make testing turnaround extra environment friendly and enhance security.

16 October, 2020 Aberdeen clinical-stage biotechnology firm NovaBiotics secures £1 million in funding from Innovate UK, permitting the corporate to start medical research for Nylexa, a probably game-changing remedy for the remedy of Covid-19.

28 October, 2020 A multi-million pound analysis challenge is introduced to assist scientists throughout the UK entry the info they want extra simply to assist develop potential therapies and coverings for Covid-19. Experts from the schools of Dundee, Edinburgh and Nottingham, together with Public Health England, will construct the infrastructure for CO-CONNECT, a £4 million UK-wide initiative to help analysis into the Covid-19 antibody response, by connecting Covid-19 information derived from affected person blood samples.

2 December, 2020 The UK grew to become the primary nation to present approval to be used of the Pfizer–BioNTech vaccine.

8 December, 2020 The first vaccine is rolled out within the UK with Margaret Keenan, 90, receiving a dose in Coventry.

30 December, 2020 The Oxford/AstraZeneca vaccine is authorised to be used within the UK.

8 January 2021 The Moderna vaccine turns into the third vaccine to be authorised within the UK.

12 January, 2021: Unique lateral circulate know-how, related to Covid-19 testing, developed and confirmed in Scotland, is submitted for UK patent safety by Glasgow-based agency Coronex.

The know-how has been demonstrated to detect SARS-CoV-2 antibodies particularly and sensitively, and it may be tailored quickly to detect antibodies to any new SARS-CoV-2 viral mutations that come up.

28 January, 2021 French biotech Valneva introduced it had began manufacturing a Covid-19 vaccine at its plant in Livingston, West Lothian, a month after beginning medical trials.

The UK Government initially ordered 60 million doses of the VLA2001 vaccine after which elevated the quantity to 100 million.

19 March, 2021 A easy check to establish sufferers at elevated threat of dying from Covid-19 receives a funding grant made by the University of Dundee.

Professor James Chalmers, from the college’s School of Medicine, is awarded £32,000 to develop a check to measure ranges of calprotectin, a possible indicator in Covid-19 mortality.

28 May, 2021 The Janssen vaccine grew to become the fourth such remedy to be given the inexperienced gentle within the UK.

13 September, 2021 The UK Government cancels its contract with French biotech Valneva for 100 million doses of vaccine.

Whitehall stated there had been a breach of settlement, which the agency strenuously denied.

15 October, 2021 The Office for National Statistics states that the share of individuals testing optimistic for Covid-19 in Scotland continues to lower.

In the week ending 9 October, 2021, the division estimated that 66,600 folks in Scotland had Covid-19, equating to about 1 in 80 folks.

This article first appeared in The Scotsman’s Life Sciences 2021 complement. A digital model may be discovered here.

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By Seth A. Dunbar

Seth A. Dunbar leads clinical research study operations and quality & compliance. His is experienced working with teams to help drug sponsors better leverage eSource data. With 10+ years of experience Seth brings expertise developing eClinical services that integrate data and technology to help companies optimise study execution.

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